This way, you can be right at your cutter moving the carriage around in very tiny increments. Note, it's highly helpful for anyone doing this to have a USB numeric keypad (just the numbers).

I aligned the laser to the reg mark as instructed. Ok, so I was able to make the registration mark. Causation and correlation aside, it's my guess that the Keyspan made the difference, as nothing else changed. I installed the Keyspan, just to be sure I wasn't getting some odd interference, and this part worked. With the USB connection, I could not even get the calibration util from Signcut to make the registration mark it needed for the laserpoint calibration. I already had the Keyspan just in case, as I was having no issues cutting vinyl. I put the pen plotter in the LP24, and Signcut's calibration utility was able to make a registration mark on a piece of A4 paper using the plotter pen, but weirdly, this only worked once I removed the USB connection to the cutter and installed a Keyspan USB to serial connector.

Here's what I am working with: I have a Laserpoint 24, Sign Cut Productivity Pro and I also have Illustrator CS3, SignBlazer (latest version) and Inkscape. Ok, I am modifying this post since nobody's answered my previous and somewhat harried entry. But, if you want to read my tortured process before I found out how to ContourCut using Paco's technique, be my guest! Update: Paco's excellent thread on contour cutting helped me get this working, using the 3-point calibration in SignCut.

Signcut pro registration